Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice

Charles B. Wright; Hironori Uehara; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Shuichiro Hirahara; Ryan D. Makin; Ivana Apicella; Felipe Pereira; Yosuke Nagasaka; Siddharth Narendran; Shinichi Fukuda; Romulo Albuquerque; Benjamin J. Fowler; Ana Bastos-Carvalho; Philippe Georgel; Izuho Hatada; Bo Chang; Nagaraj Kerur; Balamurali K. Ambati; Jayakrishna Ambati; Bradley D. Gelfand

doi:10.1073/pnas.1909761117

Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice

Charles B. Wright
, Hironori Uehara
, Younghee Kim
, Tetsuhiro Yasuma
, Reo Yasuma
, Shuichiro Hirahara
, Ryan D. Makin
, Ivana Apicella
, Felipe Pereira
, Yosuke Nagasaka
, Siddharth Narendran
, Shinichi Fukuda
, Romulo Albuquerque
, Benjamin J. Fowler
, Ana Bastos-Carvalho
, Philippe Georgel
, Izuho Hatada
, Bo Chang
, Nagaraj Kerur
, Balamurali K. Ambati

Jayakrishna Ambati, Bradley D. Gelfand

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2579-2587
Number of pages	9
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	117
Issue number	5
DOIs	https://doi.org/10.1073/pnas.1909761117
State	Published - Feb 4 2020
Externally published	Yes

ASJC Scopus Subject Areas

General

Keywords

Choroidal neovascularization
Dicer
Inflammasome
Retina

Access to Document

10.1073/pnas.1909761117

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Wright, C. B., Uehara, H., Kim, Y., Yasuma, T., Yasuma, R., Hirahara, S., Makin, R. D., Apicella, I., Pereira, F., Nagasaka, Y., Narendran, S., Fukuda, S., Albuquerque, R., Fowler, B. J., Bastos-Carvalho, A., Georgel, P., Hatada, I., Chang, B., Kerur, N., ... Gelfand, B. D. (2020). Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. Proceedings of the National Academy of Sciences of the United States of America, 117(5), 2579-2587. https://doi.org/10.1073/pnas.1909761117

Wright, CB, Uehara, H, Kim, Y, Yasuma, T, Yasuma, R, Hirahara, S, Makin, RD, Apicella, I, Pereira, F, Nagasaka, Y, Narendran, S, Fukuda, S, Albuquerque, R, Fowler, BJ, Bastos-Carvalho, A, Georgel, P, Hatada, I, Chang, B, Kerur, N, Ambati, BK, Ambati, J & Gelfand, BD 2020, 'Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 5, pp. 2579-2587. https://doi.org/10.1073/pnas.1909761117

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keywords = "Choroidal neovascularization, Dicer, Inflammasome, Retina",

author = "Wright, \{Charles B.\} and Hironori Uehara and Younghee Kim and Tetsuhiro Yasuma and Reo Yasuma and Shuichiro Hirahara and Makin, \{Ryan D.\} and Ivana Apicella and Felipe Pereira and Yosuke Nagasaka and Siddharth Narendran and Shinichi Fukuda and Romulo Albuquerque and Fowler, \{Benjamin J.\} and Ana Bastos-Carvalho and Philippe Georgel and Izuho Hatada and Bo Chang and Nagaraj Kerur and Ambati, \{Balamurali K.\} and Jayakrishna Ambati and Gelfand, \{Bradley D.\}",

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doi = "10.1073/pnas.1909761117",

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AU - Wright, Charles B.

AU - Uehara, Hironori

AU - Kim, Younghee

AU - Yasuma, Tetsuhiro

AU - Yasuma, Reo

AU - Hirahara, Shuichiro

AU - Makin, Ryan D.

AU - Apicella, Ivana

AU - Pereira, Felipe

AU - Nagasaka, Yosuke

AU - Narendran, Siddharth

AU - Fukuda, Shinichi

AU - Albuquerque, Romulo

AU - Fowler, Benjamin J.

AU - Bastos-Carvalho, Ana

AU - Georgel, Philippe

AU - Hatada, Izuho

AU - Chang, Bo

AU - Kerur, Nagaraj

AU - Ambati, Balamurali K.

AU - Ambati, Jayakrishna

AU - Gelfand, Bradley D.

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KW - Choroidal neovascularization

KW - Dicer

KW - Inflammasome

KW - Retina

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DO - 10.1073/pnas.1909761117

M3 - Article

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JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 5

ER -

Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice

ASJC Scopus Subject Areas

Keywords

Access to Document

OpenUrl availability

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