Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis

Penelope A. Rice; G. W. Boehm; J. A. Moynihan; D. L. Bellinger; S. Y. Stevens

doi:10.1016/S0889-1591(02)00016-8

Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis

Penelope A. Rice, G. W. Boehm, J. A. Moynihan, D. L. Bellinger, S. Y. Stevens

Anatomy Division

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Abstract

Here, we investigated the effects of sympathectomy on systemic bacterial loads following infection with Listeria monocytogenes, and on innate and specific immune responses in the peritoneum. Sympathectomy decreased systemic bacterial loads, and increased the number of peritoneal leukocytes and the percentage of peritoneal macrophages three days postinfection. This suggests that sympathectomy-induced decreases systemic bacterial loads are associated with increased recruitment of inflammatory cells into tissues during the innate immune response.

Original language	English
Pages (from-to)	654-662
Number of pages	9
Journal	Brain, Behavior, and Immunity
Volume	16
Issue number	6
DOIs	https://doi.org/10.1016/S0889-1591(02)00016-8
State	Published - 2002

ASJC Scopus Subject Areas

Immunology
Endocrine and Autonomic Systems
Behavioral Neuroscience

Keywords

Listeria monocytogenes
Macrophages
Peritoneum
Sympathectomy

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title = "Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis",

abstract = "Here, we investigated the effects of sympathectomy on systemic bacterial loads following infection with Listeria monocytogenes, and on innate and specific immune responses in the peritoneum. Sympathectomy decreased systemic bacterial loads, and increased the number of peritoneal leukocytes and the percentage of peritoneal macrophages three days postinfection. This suggests that sympathectomy-induced decreases systemic bacterial loads are associated with increased recruitment of inflammatory cells into tissues during the innate immune response.",

keywords = "Listeria monocytogenes, Macrophages, Peritoneum, Sympathectomy",

author = "Rice, {Penelope A.} and Boehm, {G. W.} and Moynihan, {J. A.} and Bellinger, {D. L.} and Stevens, {S. Y.}",

note = "Funding Information: I thank the following people for technical assistance: John Housel, Tracey Smith, Sandra Lee, Dr. Barbara Kruszewska, and Dr. Kelley Madden. I would also like to thank Dr. Jeffrey Hasday for editorial assistance. This work was supported by NIMH grant number R37MH42076.",

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AU - Rice, Penelope A.

AU - Boehm, G. W.

AU - Moynihan, J. A.

AU - Bellinger, D. L.

AU - Stevens, S. Y.

N1 - Funding Information: I thank the following people for technical assistance: John Housel, Tracey Smith, Sandra Lee, Dr. Barbara Kruszewska, and Dr. Kelley Madden. I would also like to thank Dr. Jeffrey Hasday for editorial assistance. This work was supported by NIMH grant number R37MH42076.

PY - 2002

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N2 - Here, we investigated the effects of sympathectomy on systemic bacterial loads following infection with Listeria monocytogenes, and on innate and specific immune responses in the peritoneum. Sympathectomy decreased systemic bacterial loads, and increased the number of peritoneal leukocytes and the percentage of peritoneal macrophages three days postinfection. This suggests that sympathectomy-induced decreases systemic bacterial loads are associated with increased recruitment of inflammatory cells into tissues during the innate immune response.

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KW - Listeria monocytogenes

KW - Macrophages

KW - Peritoneum

KW - Sympathectomy

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Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis

Abstract

ASJC Scopus Subject Areas

Keywords

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