Cerebral vasospasm following subarachnoid hemorrhage: Time for a new world of thought

Ryszard M. Pluta; Jacob Hansen-Schwartz; Jens Dreier; Peter Vajkoczy; R. Loch Macdonald; Shigeru Nishizawa; Hideotoshi Kasuya; George Wellman; Emanuela Keller; Alois Zauner; Nicholas Dorsch; Joseph Clark; Shigeki Ono; Talat Kiris; Peter Leroux; John H. Zhang

doi:10.1179/174313209X393564

Cerebral vasospasm following subarachnoid hemorrhage: Time for a new world of thought

Ryszard M. Pluta, Jacob Hansen-Schwartz, Jens Dreier, Peter Vajkoczy, R. Loch Macdonald, Shigeru Nishizawa, Hideotoshi Kasuya, George Wellman, Emanuela Keller, Alois Zauner, Nicholas Dorsch, Joseph Clark, Shigeki Ono, Talat Kiris, Peter Leroux, John H. Zhang

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Abstract

Objective: Delayed cerebral vasospasm has long been recognized as an important cause of poor outcome after an otherwise successful treatment of a ruptured intracranial aneurysm, but it remains a pathophysiological enigma despite intensive research for more than half a century. Method: Summarized in this review are highlights of research from North America, Europe and Asia reflecting recent advances in the understanding of delayed ischemic deficit. Result: It will focus on current accepted mechanisms and on new frontiers in vasospasm research. Conclusion: A key issue is the recognition of events other than arterial narrowing such as early brain injury and cortical spreading depression and of their contribution to overall mortality and morbidity. © 2009 W. S. Maney & Son Ltd.

Original language	English
Pages (from-to)	151-158
Number of pages	8
Journal	Neurological Research
Volume	31
Issue number	2
DOIs	https://doi.org/10.1179/174313209X393564
State	Published - Mar 2009

ASJC Scopus Subject Areas

Neurology
Clinical Neurology

Keywords

Early brain injury
Subarachnoid hemorrhage
Vasospasm
Subarachnoid Hemorrhage/complications
Vasospasm, Intracranial/epidemiology
Animals
Cerebral Cortex/pathology
Humans
International Cooperation
Cortical Spreading Depression/physiology
Vasoconstriction/physiology

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Pluta, R. M., Hansen-Schwartz, J., Dreier, J., Vajkoczy, P., Macdonald, R. L., Nishizawa, S., Kasuya, H., Wellman, G., Keller, E., Zauner, A., Dorsch, N., Clark, J., Ono, S., Kiris, T., Leroux, P., & Zhang, J. H. (2009). Cerebral vasospasm following subarachnoid hemorrhage: Time for a new world of thought. Neurological Research, 31(2), 151-158. https://doi.org/10.1179/174313209X393564

Pluta, RM, Hansen-Schwartz, J, Dreier, J, Vajkoczy, P, Macdonald, RL, Nishizawa, S, Kasuya, H, Wellman, G, Keller, E, Zauner, A, Dorsch, N, Clark, J, Ono, S, Kiris, T, Leroux, P & Zhang, JH 2009, 'Cerebral vasospasm following subarachnoid hemorrhage: Time for a new world of thought', Neurological Research, vol. 31, no. 2, pp. 151-158. https://doi.org/10.1179/174313209X393564

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Cerebral vasospasm following subarachnoid hemorrhage: Time for a new world of thought

Abstract

ASJC Scopus Subject Areas

Keywords

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