CCR5 Governs DNA damage repair and breast cancer stem cell expansion

Xuanmao Jiao; Marco A. Velasco-Velazquez; Min Wang; Zhiping Li; Hallgeir Rui; Amy R. Peck; James E. Korkola; Xuelian Chen; Shaohua Xu; James B. DuHadaway; Sandra Guerrero-Rodriguez; Sankar Addya; Daniela Sicoli; Zhaomei Mu; Gang Zhang; Andres Stucky; Xi Zhang; Massimo Cristofanilli; Alessandro Fatatis; Joe W. Gray; Jiang F. Zhong; George C. Prendergast; Richard G. Pestell

doi:10.1158/0008-5472.CAN-17-0915

CCR5 Governs DNA damage repair and breast cancer stem cell expansion

Xuanmao Jiao, Marco A. Velasco-Velazquez, Min Wang, Zhiping Li, Hallgeir Rui, Amy R. Peck, James E. Korkola, Xuelian Chen, Shaohua Xu, James B. DuHadaway, Sandra Guerrero-Rodriguez, Sankar Addya, Daniela Sicoli, Zhaomei Mu, Gang Zhang, Andres Stucky, Xi Zhang, Massimo Cristofanilli, Alessandro Fatatis, Joe W. GrayJiang F. Zhong, George C. Prendergast, Richard G. Pestell

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1657-1671
Number of pages	15
Journal	Cancer Research
Volume	78
Issue number	7
DOIs	https://doi.org/10.1158/0008-5472.CAN-17-0915
State	Published - Apr 1 2018
Externally published	Yes

ASJC Scopus Subject Areas

Oncology
Cancer Research

Keywords

Epithelial Cells/metabolism
Neoplasm Transplantation
DNA Damage/genetics
Piperazines/pharmacology
Humans
Gene Expression Regulation, Neoplastic
Neoplastic Stem Cells/metabolism
Phosphatidylinositol 3-Kinases/metabolism
Cell Transformation, Neoplastic/genetics
CCR5 Receptor Antagonists/pharmacology
Transplantation, Heterologous
Maraviroc/pharmacology
Pyrimidines/pharmacology
Antineoplastic Agents/pharmacology
Animals
Mice, Nude
Cell Line, Tumor
DNA Repair/immunology
Cell Proliferation/genetics
Female
Breast Neoplasms/genetics
Mice
Receptors, CCR5/metabolism

Access to Document

10.1158/0008-5472.CAN-17-0915

OpenUrl availability

Full text

Cite this

Jiao, X., Velasco-Velazquez, M. A., Wang, M., Li, Z., Rui, H., Peck, A. R., Korkola, J. E., Chen, X., Xu, S., DuHadaway, J. B., Guerrero-Rodriguez, S., Addya, S., Sicoli, D., Mu, Z., Zhang, G., Stucky, A., Zhang, X., Cristofanilli, M., Fatatis, A., ... Pestell, R. G. (2018). CCR5 Governs DNA damage repair and breast cancer stem cell expansion. Cancer Research, 78(7), 1657-1671. https://doi.org/10.1158/0008-5472.CAN-17-0915

Jiao, X, Velasco-Velazquez, MA, Wang, M, Li, Z, Rui, H, Peck, AR, Korkola, JE, Chen, X, Xu, S, DuHadaway, JB, Guerrero-Rodriguez, S, Addya, S, Sicoli, D, Mu, Z, Zhang, G, Stucky, A, Zhang, X, Cristofanilli, M, Fatatis, A, Gray, JW, Zhong, JF, Prendergast, GC & Pestell, RG 2018, 'CCR5 Governs DNA damage repair and breast cancer stem cell expansion', Cancer Research, vol. 78, no. 7, pp. 1657-1671. https://doi.org/10.1158/0008-5472.CAN-17-0915

@article{a3ddf65ee74440e7b509f56894bdbce2,

title = "CCR5 Governs DNA damage repair and breast cancer stem cell expansion",

keywords = "Epithelial Cells/metabolism, Neoplasm Transplantation, DNA Damage/genetics, Piperazines/pharmacology, Humans, Gene Expression Regulation, Neoplastic, Neoplastic Stem Cells/metabolism, Phosphatidylinositol 3-Kinases/metabolism, Cell Transformation, Neoplastic/genetics, CCR5 Receptor Antagonists/pharmacology, Transplantation, Heterologous, Maraviroc/pharmacology, Pyrimidines/pharmacology, Antineoplastic Agents/pharmacology, Animals, Mice, Nude, Cell Line, Tumor, DNA Repair/immunology, Cell Proliferation/genetics, Female, Breast Neoplasms/genetics, Mice, Receptors, CCR5/metabolism",

author = "Xuanmao Jiao and Velasco-Velazquez, {Marco A.} and Min Wang and Zhiping Li and Hallgeir Rui and Peck, {Amy R.} and Korkola, {James E.} and Xuelian Chen and Shaohua Xu and DuHadaway, {James B.} and Sandra Guerrero-Rodriguez and Sankar Addya and Daniela Sicoli and Zhaomei Mu and Gang Zhang and Andres Stucky and Xi Zhang and Massimo Cristofanilli and Alessandro Fatatis and Gray, {Joe W.} and Zhong, {Jiang F.} and Prendergast, {George C.} and Pestell, {Richard G.}",

note = "Publisher Copyright: {\textcopyright} 2018 American Association for Cancer Research.",

year = "2018",

month = apr,

day = "1",

doi = "10.1158/0008-5472.CAN-17-0915",

language = "English",

volume = "78",

pages = "1657--1671",

journal = "Cancer Research",

issn = "0008-5472",

number = "7",

}

TY - JOUR

T1 - CCR5 Governs DNA damage repair and breast cancer stem cell expansion

AU - Jiao, Xuanmao

AU - Velasco-Velazquez, Marco A.

AU - Wang, Min

AU - Li, Zhiping

AU - Rui, Hallgeir

AU - Peck, Amy R.

AU - Korkola, James E.

AU - Chen, Xuelian

AU - Xu, Shaohua

AU - DuHadaway, James B.

AU - Guerrero-Rodriguez, Sandra

AU - Addya, Sankar

AU - Sicoli, Daniela

AU - Mu, Zhaomei

AU - Zhang, Gang

AU - Stucky, Andres

AU - Zhang, Xi

AU - Cristofanilli, Massimo

AU - Fatatis, Alessandro

AU - Gray, Joe W.

AU - Zhong, Jiang F.

AU - Prendergast, George C.

AU - Pestell, Richard G.

PY - 2018/4/1

Y1 - 2018/4/1

KW - Epithelial Cells/metabolism

KW - Neoplasm Transplantation

KW - DNA Damage/genetics

KW - Piperazines/pharmacology

KW - Humans

KW - Gene Expression Regulation, Neoplastic

KW - Neoplastic Stem Cells/metabolism

KW - Phosphatidylinositol 3-Kinases/metabolism

KW - Cell Transformation, Neoplastic/genetics

KW - CCR5 Receptor Antagonists/pharmacology

KW - Transplantation, Heterologous

KW - Maraviroc/pharmacology

KW - Pyrimidines/pharmacology

KW - Antineoplastic Agents/pharmacology

KW - Animals

KW - Mice, Nude

KW - Cell Line, Tumor

KW - DNA Repair/immunology

KW - Cell Proliferation/genetics

KW - Female

KW - Breast Neoplasms/genetics

KW - Mice

KW - Receptors, CCR5/metabolism

UR - http://www.scopus.com/inward/record.url?scp=85047155981&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047155981&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/adfdb48e-f0be-3079-b6bb-79fff9f2ae83/

U2 - 10.1158/0008-5472.CAN-17-0915

DO - 10.1158/0008-5472.CAN-17-0915

M3 - Article

C2 - 29358169

AN - SCOPUS:85047155981

SN - 0008-5472

VL - 78

SP - 1657

EP - 1671

JO - Cancer Research

JF - Cancer Research

IS - 7

ER -

CCR5 Governs DNA damage repair and breast cancer stem cell expansion

ASJC Scopus Subject Areas

Keywords

Access to Document

OpenUrl availability

Other files and links

Cite this