Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells

Saied Mirshahidi; Troy G. Shields; Rosalia De Necochea-Campion; Xiangpeng Yuan; Ata Janjua; Nadine L. Williams; Hamid R. Mirshahidi; Mark E. Reeves; Penelope Duerksen-Hughes; Lee M. Zuckerman

doi:10.1097/CORR.0000000000001510

Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells

Saied Mirshahidi
, Troy G. Shields
, Rosalia De Necochea-Campion
, Xiangpeng Yuan
, Ata Janjua
, Nadine L. Williams
, Hamid R. Mirshahidi
, Mark E. Reeves
, Penelope Duerksen-Hughes
, Lee M. Zuckerman

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	180-194
Number of pages	15
Journal	Clinical Orthopaedics and Related Research
Volume	479
Issue number	1
DOIs	https://doi.org/10.1097/CORR.0000000000001510
State	Published - Jan 1 2021

ASJC Scopus Subject Areas

Surgery
Orthopedics and Sports Medicine

Keywords

Lidocaine/pharmacology
Reactive Oxygen Species/metabolism
Bupivacaine/pharmacology
Antineoplastic Agents/pharmacology
Animals
Humans
Apoptosis/drug effects
Cell Line, Tumor
Rats
Apoptosis Regulatory Proteins/metabolism
Osteosarcoma/drug therapy
Bone Neoplasms/drug therapy

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@article{9f17834e3fe647f2864b0612c8df71fb,

title = "Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells",

keywords = "Lidocaine/pharmacology, Reactive Oxygen Species/metabolism, Bupivacaine/pharmacology, Antineoplastic Agents/pharmacology, Animals, Humans, Apoptosis/drug effects, Cell Line, Tumor, Rats, Apoptosis Regulatory Proteins/metabolism, Osteosarcoma/drug therapy, Bone Neoplasms/drug therapy",

author = "Saied Mirshahidi and Shields, \{Troy G.\} and \{De Necochea-Campion\}, Rosalia and Xiangpeng Yuan and Ata Janjua and Williams, \{Nadine L.\} and Mirshahidi, \{Hamid R.\} and Reeves, \{Mark E.\} and Penelope Duerksen-Hughes and Zuckerman, \{Lee M.\}",

note = "Copyright {\textcopyright} 2020 by the Association of Bone and Joint Surgeons.",

year = "2021",

month = jan,

day = "1",

doi = "10.1097/CORR.0000000000001510",

language = "English",

volume = "479",

pages = "180--194",

journal = "Clinical Orthopaedics and Related Research",

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TY - JOUR

T1 - Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells

AU - Mirshahidi, Saied

AU - Shields, Troy G.

AU - De Necochea-Campion, Rosalia

AU - Yuan, Xiangpeng

AU - Janjua, Ata

AU - Williams, Nadine L.

AU - Mirshahidi, Hamid R.

AU - Reeves, Mark E.

AU - Duerksen-Hughes, Penelope

AU - Zuckerman, Lee M.

PY - 2021/1/1

Y1 - 2021/1/1

KW - Lidocaine/pharmacology

KW - Reactive Oxygen Species/metabolism

KW - Bupivacaine/pharmacology

KW - Antineoplastic Agents/pharmacology

KW - Animals

KW - Humans

KW - Apoptosis/drug effects

KW - Cell Line, Tumor

KW - Rats

KW - Apoptosis Regulatory Proteins/metabolism

KW - Osteosarcoma/drug therapy

KW - Bone Neoplasms/drug therapy

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UR - https://www.scopus.com/pages/publications/85099172357#tab=citedBy

UR - https://www.mendeley.com/catalogue/f47c9485-2892-3c2d-9217-a60303bb2d7f/

U2 - 10.1097/CORR.0000000000001510

DO - 10.1097/CORR.0000000000001510

M3 - Article

C2 - 33009230

SN - 0009-921X

VL - 479

SP - 180

EP - 194

JO - Clinical Orthopaedics and Related Research

JF - Clinical Orthopaedics and Related Research

IS - 1

ER -

Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells

ASJC Scopus Subject Areas

Keywords

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