@article{1e83ed7f56fb4e08ad950414ded92cc9,
title = "Brusatol-mediated induction of leukemic cell differentiation and G1 arrest is associated with down-regulation of c-myc",
keywords = "Brusatol, Cell differentiation, Cytotoxicity, Quassinoids, c-MYC, Cell Differentiation/drug effects, Down-Regulation, Humans, Brucea, RNA, Neoplasm/metabolism, Immunophenotyping, Lymphocytes/metabolism, Gene Expression Regulation, Leukemic, Quassins/pharmacology, Reverse Transcriptase Polymerase Chain Reaction, Flow Cytometry, Plant Preparations, G1 Phase/drug effects, Proto-Oncogene Proteins c-myc/genetics, RNA, Messenger/analysis, Phytotherapy, Tumor Cells, Cultured, DNA Primers/chemistry, Leukemia, Myeloid/metabolism",
author = "E. Mata-Greenwood and M. Cuendet and D. Sher and D. Gustin and W. Stock and Pezzuto, \{J. M.\}",
note = "Funding Information: Some of the data described in this manuscript were presented at the 91st Annual AACR Meeting, San Francisco, CA, April 1–5, 2000. The authors are grateful to the Drug Synthesis and Chemistry Branch, Developmental Therapeutics Program, Division of Treatment, National Cancer Institute, for the provision of bruceantin and to Dr K Hagen of the Research Resources Center (UIC) for analysis of samples by flow cytometry. Support for this work was provided by grant P01 CA48112 awarded by the National Cancer Institute.",
year = "2002",
month = nov,
day = "1",
doi = "10.1038/sj.leu.2402696",
language = "English",
volume = "16",
pages = "2275--2284",
journal = "Leukemia",
issn = "0887-6924",
number = "11",
}