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Bronchial Thermoplasty: A Decade of Experience: State of the Art

  • Laren D. Tan
  • , Ken Y. Yoneda
  • , Samuel Louie
  • , D. Kyle Hogarth
  • , Mario Castro

Research output: Contribution to journalArticlepeer-review

Abstract

Bronchial thermoplasty (BT) delivers targeted radiofrequency energy to bronchial airway walls and results in the partial ablation of the airway smooth muscle that is responsible for bronchoconstriction. It is approved for the treatment of severe persistent asthma. Multiple, large clinical trials including a recent “real-world” study demonstrate significant improvements in asthma-related quality of life, reduction in asthma exacerbations, emergency department visits, and hospitalizations after BT that is sustained out to 5 years. In this article, we review the state of the art of BT treatment in severe persistent asthma and share a decade of BT research and clinical experience. We share our personal experience and introduce the three “I”s (identification, implementation, and intense follow-up) that we believe promote successful patient outcomes and help build a successful BT program.

Original languageEnglish
Pages (from-to)71-80
Number of pages10
JournalJournal of Allergy and Clinical Immunology: In Practice
Volume7
Issue number1
DOIs
StatePublished - Jan 2019

ASJC Scopus Subject Areas

  • Immunology and Allergy

Keywords

  • Airway smooth muscle
  • Asthma
  • Bronchial thermoplasty
  • Bronchoscopy
  • Conscious sedation
  • Moderate sedation
  • Radiofrequency energy
  • Severe asthma
  • Bronchial Thermoplasty/methods
  • Humans
  • Treatment Outcome
  • Clinical Trials as Topic
  • Myocytes, Smooth Muscle/physiology
  • Bronchi/pathology
  • Disease Progression
  • Bronchoconstriction
  • Radiofrequency Ablation
  • Radiofrequency Therapy/methods
  • Quality of Life
  • Asthma/therapy

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