Botulinum Toxin: Preparations for Clinical Use, Immunogenicity, Side Effects, and Safety Profile

Khashayar Dashtipour; Farzin Pedouim

doi:10.1055/s-0035-1571213

Botulinum Toxin: Preparations for Clinical Use, Immunogenicity, Side Effects, and Safety Profile

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Abstract

Botulinum toxin (BoNT) formulations are being used for a variety of medical applications. The use of BoNT preparations is continuously expanding with new formulations and indications. Of the seven antigenically distinct BoNTs, only two serotypes, type A and type B are commonly available for therapeutic use. The four available BoNT products are not equivalent and the knowledge of their formulations is crucial for product selection, avoidance of medication errors, therapeutic efficacy and safety. Generally, BoNT injection is a safe procedure when administered by an experienced injector. Side effects are always transient, and in the majority of cases they are mild and tolerable.

Original language	English
Pages (from-to)	29-33
Number of pages	5
Journal	Seminars in Neurology
Volume	36
Issue number	1
DOIs	https://doi.org/10.1055/s-0035-1571213
State	Published - Jan 2016

ASJC Scopus Subject Areas

Neurology
Clinical Neurology

Keywords

AbobotulinumtoxinA
IncobotulinumtoxinA
OnabotulinumtoxinA
RimabotulinumtoxinB
Humans
Immunogenetic Phenomena/drug effects
Botulinum Toxins/administration & dosage
Animals
Antibody Formation/drug effects
Drug Compounding
Pain/drug therapy
Muscle Weakness/chemically induced
Migraine Disorders/drug therapy

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abstract = "Botulinum toxin (BoNT) formulations are being used for a variety of medical applications. The use of BoNT preparations is continuously expanding with new formulations and indications. Of the seven antigenically distinct BoNTs, only two serotypes, type A and type B are commonly available for therapeutic use. The four available BoNT products are not equivalent and the knowledge of their formulations is crucial for product selection, avoidance of medication errors, therapeutic efficacy and safety. Generally, BoNT injection is a safe procedure when administered by an experienced injector. Side effects are always transient, and in the majority of cases they are mild and tolerable.",

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Botulinum Toxin: Preparations for Clinical Use, Immunogenicity, Side Effects, and Safety Profile

Abstract

ASJC Scopus Subject Areas

Keywords

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