@article{fb87221ce5e34834b9d6cdd3f7a85496,
title = "Automated core-penumbra quantification in neonatal ischemic brain injury",
keywords = "MRI, animal models, brain ischemia, cerebrovascular disease, diffusion-weighted MRI, focal ischemia, global ischemia, neonatal ischemia, pediatric stroke, perfusion-weighted MRI, Animals, Newborn, Immunohistochemistry, Brain Injuries/metabolism, Humans, Magnetic Resonance Angiography, Rats, Male, Brain Ischemia/metabolism, Animals, Female, Infant, Newborn, Diseases/metabolism, Infant, Newborn, Brain/metabolism",
author = "Nirmalya Ghosh and Xiangpeng Yuan and Turenius, \{Christine I.\} and Beatriz Tone and Kamalakar Ambadipudi and Snyder, \{Evan Y.\} and Andre Obenaus and Stephen Ashwal",
note = "Neonatal hypoxic-ischemic brain injury (HII) and arterial ischemic stroke (AIS) result in irreversibly injured (core) and salvageable (penumbral) tissue regions. Identification and reliable quantification of salvageable tissue is pivotal to any effective and safe intervention. Magnetic resonance imaging (MRI) is the current standard to distinguish core from penumbra using diffusion-perfusion mismatch (DPM).",
year = "2012",
month = dec,
doi = "10.1038/jcbfm.2012.121",
language = "English",
volume = "32",
pages = "2161--2170",
journal = "Journal of Cerebral Blood Flow and Metabolism",
issn = "0271-678X",
number = "12",
}