Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

Otavio Cabral-Marques; Gilad Halpert; Lena F. Schimke; Yuri Ostrinski; Aristo Vojdani; Gabriela Crispim Baiocchi; Paula Paccielli Freire; Igor Salerno Filgueiras; Israel Zyskind; Miriam T. Lattin; Florian Tran; Stefan Schreiber; Alexandre H.C. Marques; Desirée Rodrigues Plaça; Dennyson Leandro M. Fonseca; Jens Y. Humrich; Antje Müller; Lasse M. Giil; Hanna Graßhoff; Anja Schumann; Alexander Hackel; Juliane Junker; Carlotta Meyer; Hans D. Ochs; Yael Bublil Lavi; Carmen Scheibenbogen; Ralf Dechend; Igor Jurisica; Kai Schulze-Forster; Jonathan I. Silverberg; Howard Amital; Jason Zimmerman; Harry Heidecke; Avi Z. Rosenberg; Gabriela Riemekasten; Yehuda Shoenfeld

doi:10.1038/s41467-022-28905-5

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

Otavio Cabral-Marques, Gilad Halpert, Lena F. Schimke, Yuri Ostrinski, Aristo Vojdani, Gabriela Crispim Baiocchi, Paula Paccielli Freire, Igor Salerno Filgueiras, Israel Zyskind, Miriam T. Lattin, Florian Tran, Stefan Schreiber, Alexandre H.C. Marques, Desirée Rodrigues Plaça, Dennyson Leandro M. Fonseca, Jens Y. Humrich, Antje Müller, Lasse M. Giil, Hanna Graßhoff, Anja SchumannAlexander Hackel, Juliane Junker, Carlotta Meyer, Hans D. Ochs, Yael Bublil Lavi, Carmen Scheibenbogen, Ralf Dechend, Igor Jurisica, Kai Schulze-Forster, Jonathan I. Silverberg, Howard Amital, Jason Zimmerman, Harry Heidecke, Avi Z. Rosenberg, Gabriela Riemekasten, Yehuda Shoenfeld

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	1220
Journal	Nature Communications
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/s41467-022-28905-5
State	Published - Mar 9 2022
Externally published	Yes

ASJC Scopus Subject Areas

General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Physics and Astronomy

Keywords

Autoantibodies/blood
Autoimmunity
Severity of Illness Index
Multivariate Analysis
Cross-Sectional Studies
Humans
Male
COVID-19/blood
Receptors, CXCR3/immunology
Machine Learning
Receptors, G-Protein-Coupled/immunology
SARS-CoV-2
Biomarkers/blood
Female
Renin-Angiotensin System/immunology
Receptor, Angiotensin, Type 1/immunology

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Cabral-Marques, O., Halpert, G., Schimke, L. F., Ostrinski, Y., Vojdani, A., Baiocchi, G. C., Freire, P. P., Filgueiras, I. S., Zyskind, I., Lattin, M. T., Tran, F., Schreiber, S., Marques, A. H. C., Plaça, D. R., Fonseca, D. L. M., Humrich, J. Y., Müller, A., Giil, L. M., Graßhoff, H., ... Shoenfeld, Y. (2022). Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity. Nature Communications, 13(1), Article 1220. https://doi.org/10.1038/s41467-022-28905-5

Cabral-Marques, O, Halpert, G, Schimke, LF, Ostrinski, Y, Vojdani, A, Baiocchi, GC, Freire, PP, Filgueiras, IS, Zyskind, I, Lattin, MT, Tran, F, Schreiber, S, Marques, AHC, Plaça, DR, Fonseca, DLM, Humrich, JY, Müller, A, Giil, LM, Graßhoff, H, Schumann, A, Hackel, A, Junker, J, Meyer, C, Ochs, HD, Lavi, YB, Scheibenbogen, C, Dechend, R, Jurisica, I, Schulze-Forster, K, Silverberg, JI, Amital, H, Zimmerman, J, Heidecke, H, Rosenberg, AZ, Riemekasten, G & Shoenfeld, Y 2022, 'Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity', Nature Communications, vol. 13, no. 1, 1220. https://doi.org/10.1038/s41467-022-28905-5

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AU - Plaça, Desirée Rodrigues

AU - Fonseca, Dennyson Leandro M.

AU - Humrich, Jens Y.

AU - Müller, Antje

AU - Giil, Lasse M.

AU - Graßhoff, Hanna

AU - Schumann, Anja

AU - Hackel, Alexander

AU - Junker, Juliane

AU - Meyer, Carlotta

AU - Ochs, Hans D.

AU - Lavi, Yael Bublil

AU - Scheibenbogen, Carmen

AU - Dechend, Ralf

AU - Jurisica, Igor

AU - Schulze-Forster, Kai

AU - Silverberg, Jonathan I.

AU - Amital, Howard

AU - Zimmerman, Jason

AU - Heidecke, Harry

AU - Rosenberg, Avi Z.

AU - Riemekasten, Gabriela

AU - Shoenfeld, Yehuda

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Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

ASJC Scopus Subject Areas

Keywords

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