Skip to main navigation Skip to search Skip to main content

Augmented osteogenic responses in human aortic valve cells exposed to oxLDL and TLR4 agonist: A mechanistic role of Notch1 and NF-κB interaction

  • Qingchun Zeng
  • , Rui Song
  • , Lihua Ao
  • , Dingli Xu
  • , Neil Venardos
  • , David A. Fullerton
  • , Xianzhong Meng

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere95400
JournalPLoS ONE
Volume9
Issue number5
DOIs
StatePublished - May 8 2014
Externally publishedYes

ASJC Scopus Subject Areas

  • General

Keywords

  • Cardiomyopathies/metabolism
  • Up-Regulation/drug effects
  • Toll-Like Receptor 4/agonists
  • Heart Valve Diseases/metabolism
  • Humans
  • Middle Aged
  • Male
  • Lipopolysaccharides/pharmacology
  • Signal Transduction/drug effects
  • Bicuspid Aortic Valve Disease
  • Heart Defects, Congenital/metabolism
  • Calcinosis/metabolism
  • Bone Morphogenetic Protein 2/metabolism
  • Osteogenesis/drug effects
  • Aortic Valve/drug effects
  • Female
  • Aged
  • NF-kappa B/metabolism
  • Lipoproteins, LDL/pharmacology
  • Receptor, Notch1/metabolism

Cite this