Aphthous ulcers associated with imiquimod and the treatment of actinic cheilitis

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Abstract

Our case series report is the first documented depiction of the appearance of aphthous ulcers secondary to imiquimod application. This case series presentation discusses the underlying pathophysiology of aphthous ulcer development and imiquimod therapy in terms of the stimulation of proinflammatory cytokines, such as tumor necrosis factor α (TNF-α). The literature review suggests more than just a mere coincidence for the development of aphthous ulcers subsequent to the treatment of actinic cheilitis with imiquimod application.

Original languageEnglish
Pages (from-to)S35-S37
JournalJournal of the American Academy of Dermatology
Volume52
Issue number2 SUPPL.
DOIs
StatePublished - Feb 2005

ASJC Scopus Subject Areas

  • Dermatology

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