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Anaphylactic-like reaction from trimethoprim-sulfamethoxazole in a patient with AIDS

Research output: Contribution to journalArticlepeer-review

Abstract

We report a patient with AIDS who had an anaphylactic-like reaction from trimethoprim-sulfamethoxazole. Clinical suspicion of anaphylaxis should be considered in patients presenting with fever, hypotension, eosinophilia, rash, flushing or pulmonary infiltrates after initial exposure and re-exposure to the medication. This case highlights the need for healthcare professionals to be reminded of the association between this unusual antibiotic reaction resembling sepsis and HIV disease.

Original languageEnglish
Pages (from-to)595-597
Number of pages3
JournalInternational Journal of STD and AIDS
Volume27
Issue number7
DOIs
StatePublished - Jun 2016
Externally publishedYes

ASJC Scopus Subject Areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

Keywords

  • AIDS
  • HIV
  • Trimethoprim-sulfamethoxazole
  • adverse drug reaction
  • anaphylaxis
  • sepsis
  • AIDS-Related Opportunistic Infections/prevention & control
  • Acquired Immunodeficiency Syndrome/complications
  • Anti-Bacterial Agents/administration & dosage
  • Humans
  • Drug Hypersensitivity
  • Pneumonia, Pneumocystis/drug therapy
  • Fever/etiology
  • Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage
  • Anaphylaxis
  • Transgender Persons
  • Adult
  • Female

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