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Alcohol inhibits osteopontin-dependent transforming growth factor-β1 expression in human mesenchymal stem cells

  • Joseph Driver
  • , Cynthia E. Weber
  • , John J. Callaci
  • , Anai N. Kothari
  • , Matthew A. Zapf
  • , Philip M. Roper
  • , Dariusz Borys
  • , Carrie A. Franzen
  • , Gopal N. Gupta
  • , Philip Y. Wai
  • , Jiwang Zhang
  • , Mitchell F. Denning
  • , Paul C. Kuo
  • , Zhiyong Mi

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)9959-9973
Number of pages15
JournalJournal of Biological Chemistry
Volume290
Issue number16
DOIs
StatePublished - Apr 17 2015
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Keywords

  • Tibial Fractures/genetics
  • Phosphorylation
  • Signal Transduction
  • Transforming Growth Factor beta1/antagonists & inhibitors
  • Humans
  • Mice, Inbred C57BL
  • Gene Expression Regulation
  • Ethanol/adverse effects
  • Male
  • Fracture Healing/drug effects
  • Aptamers, Nucleotide/genetics
  • Tibia/drug effects
  • Osteopontin/metabolism
  • Kruppel-Like Transcription Factors/antagonists & inhibitors
  • Animals
  • Mesenchymal Stem Cells/drug effects
  • Cell Differentiation
  • Mice
  • Luciferases/genetics

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