TY - JOUR
T1 - Adrenochrome and related oxidative metabolites of catecholamines
T2 - Effects on dopamine neurons and receptor binding profiles
AU - Krstenansky, John L.
AU - Xu, Dan
AU - Leitzke, Rolf
AU - Saldivar, April
AU - Gevorkian, Ruzanna
AU - Shi, Wei Xing
N1 - Funding Information:
To test whether adrenochrome acts in part through central dopamine (DA) systems, we made single-cell recordings from DA neurons in the ventral tegmental area in chloral hydrate-anesthetized rats. We also screened for potential binding sites of adrenochrome through the National Institute of Mental Health's Psychoactive Drug Screening Program (Contract # HHSN-271-2008-00025-C).
PY - 2011/12
Y1 - 2011/12
KW - Protein Binding/drug effects
KW - Action Potentials/drug effects
KW - Amphetamine/pharmacology
KW - Rats
KW - Dopamine Agents/pharmacology
KW - Dopaminergic Neurons/drug effects
KW - Dose-Response Relationship, Drug
KW - Indoles/pharmacology
KW - Adrenochrome/pharmacology
KW - Receptors, Biogenic Amine/metabolism
KW - Animals
KW - Catecholamines/metabolism
KW - Levodopa/pharmacology
KW - Ventral Tegmental Area/cytology
UR - https://www.scopus.com/pages/publications/81955160730
UR - https://www.scopus.com/pages/publications/81955160730#tab=citedBy
UR - https://www.mendeley.com/catalogue/feadeb13-3d3a-3f09-8f23-a12f9b603049/
U2 - 10.1016/j.schres.2011.08.015
DO - 10.1016/j.schres.2011.08.015
M3 - Letter
C2 - 21906912
SN - 0920-9964
VL - 133
SP - 264
EP - 265
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 1-3
ER -