Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

Pavan Kumar Dhanyam Raju; Shriya Kane; Chandrika Gowda; Chunhua Song; Yali Ding; Jonathan Payne; Soumya Iyer; Nathalia Moreno Curry; Mary McGrath; Yevgeniya Bamme; Bihua Tan; Mario Soliman; Dhimant Desai; Arati Sharma; Kimberly J. Payne; Sinisa Dovat

doi:10.1158/1538-7445.SABCS18-4400

Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

Pavan Kumar Dhanyam Raju
, Shriya Kane
, Chandrika Gowda
, Chunhua Song
, Yali Ding
, Jonathan Payne
, Soumya Iyer
, Nathalia Moreno Curry
, Mary McGrath
, Yevgeniya Bamme
, Bihua Tan
, Mario Soliman
, Dhimant Desai
, Arati Sharma
, Kimberly J. Payne
, Sinisa Dovat

Loma Linda University

Research output: Contribution to conference › Poster › peer-review

Original language	American English
Pages	4400
Number of pages	1
DOIs	https://doi.org/10.1158/1538-7445.SABCS18-4400
State	Published - Jul 1 2019

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Biology
Oncology

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Raju, P. K. D., Kane, S., Gowda, C., Song, C., Ding, Y., Payne, J., Iyer, S., Curry, N. M., McGrath, M., Bamme, Y., Tan, B., Soliman, M., Desai, D., Sharma, A., Payne, K. J., & Dovat, S. (2019). Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL). 4400. https://doi.org/10.1158/1538-7445.SABCS18-4400

Raju, PKD, Kane, S, Gowda, C, Song, C, Ding, Y, Payne, J, Iyer, S, Curry, NM, McGrath, M, Bamme, Y, Tan, B, Soliman, M, Desai, D, Sharma, A, Payne, KJ & Dovat, S 2019, 'Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)', pp. 4400. https://doi.org/10.1158/1538-7445.SABCS18-4400

@conference{7d623ea6f61644e5bf3b265f632ac76a,

title = "Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)",

author = "Raju, \{Pavan Kumar Dhanyam\} and Shriya Kane and Chandrika Gowda and Chunhua Song and Yali Ding and Jonathan Payne and Soumya Iyer and Curry, \{Nathalia Moreno\} and Mary McGrath and Yevgeniya Bamme and Bihua Tan and Mario Soliman and Dhimant Desai and Arati Sharma and Payne, \{Kimberly J.\} and Sinisa Dovat",

note = "Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA CDC16 is one of several subunits of the anaphase-promoting complex (APC) with crucial role in cell division. Here, we show evidence that expression of CDC16 in T-ALL is modulated at the transcriptional level by oncogenic Casein Kinase II (CK2) via direct phosphorylation of Ikaros, a tumor suppressor protein and transcription factor.",

year = "2019",

month = jul,

day = "1",

doi = "10.1158/1538-7445.SABCS18-4400",

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TY - CONF

T1 - Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

AU - Raju, Pavan Kumar Dhanyam

AU - Kane, Shriya

AU - Gowda, Chandrika

AU - Song, Chunhua

AU - Ding, Yali

AU - Payne, Jonathan

AU - Iyer, Soumya

AU - Curry, Nathalia Moreno

AU - McGrath, Mary

AU - Bamme, Yevgeniya

AU - Tan, Bihua

AU - Soliman, Mario

AU - Desai, Dhimant

AU - Sharma, Arati

AU - Payne, Kimberly J.

AU - Dovat, Sinisa

N1 - Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA CDC16 is one of several subunits of the anaphase-promoting complex (APC) with crucial role in cell division. Here, we show evidence that expression of CDC16 in T-ALL is modulated at the transcriptional level by oncogenic Casein Kinase II (CK2) via direct phosphorylation of Ikaros, a tumor suppressor protein and transcription factor.

PY - 2019/7/1

Y1 - 2019/7/1

UR - https://cancerres.aacrjournals.org/content/79/13_Supplement/4400

U2 - 10.1158/1538-7445.SABCS18-4400

DO - 10.1158/1538-7445.SABCS18-4400

M3 - Poster

SP - 4400

ER -

Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

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