Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

Pavan Kumar Dhanyam Raju; Shriya Kane; Chandrika Gowda; Chunhua Song; Yali Ding; Jonathan Payne; Soumya Iyer; Nathalia Moreno Curry; Mary McGrath; Yevgeniya Bamme; Bihua Tan; Mario Soliman; Dhimant Desai; Arati Sharma; Kimberly J. Payne; Sinisa Dovat

doi:10.1158/1538-7445.SABCS18-4400

Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

Pavan Kumar Dhanyam Raju, Shriya Kane, Chandrika Gowda, Chunhua Song, Yali Ding, Jonathan Payne, Soumya Iyer, Nathalia Moreno Curry, Mary McGrath, Yevgeniya Bamme, Bihua Tan, Mario Soliman, Dhimant Desai, Arati Sharma, Kimberly J. Payne, Sinisa Dovat

Research output: Contribution to journal › Meeting abstract › peer-review

Original language	American English
Number of pages	1
Journal	Cancer Research
DOIs	https://doi.org/10.1158/1538-7445.SABCS18-4400
State	Published - Jul 1 2019

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Biology
Oncology

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Raju, P. K. D., Kane, S., Gowda, C., Song, C., Ding, Y., Payne, J., Iyer, S., Curry, N. M., McGrath, M., Bamme, Y., Tan, B., Soliman, M., Desai, D., Sharma, A., Payne, K. J., & Dovat, S. (2019). Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL). Cancer Research. https://doi.org/10.1158/1538-7445.SABCS18-4400

Raju, PKD, Kane, S, Gowda, C, Song, C, Ding, Y, Payne, J, Iyer, S, Curry, NM, McGrath, M, Bamme, Y, Tan, B, Soliman, M, Desai, D, Sharma, A, Payne, KJ & Dovat, S 2019, 'Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)', Cancer Research. https://doi.org/10.1158/1538-7445.SABCS18-4400

@article{7d623ea6f61644e5bf3b265f632ac76a,

title = "Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)",

author = "Raju, \{Pavan Kumar Dhanyam\} and Shriya Kane and Chandrika Gowda and Chunhua Song and Yali Ding and Jonathan Payne and Soumya Iyer and Curry, \{Nathalia Moreno\} and Mary McGrath and Yevgeniya Bamme and Bihua Tan and Mario Soliman and Dhimant Desai and Arati Sharma and Payne, \{Kimberly J.\} and Sinisa Dovat",

note = "Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA CDC16 is one of several subunits of the anaphase-promoting complex (APC) with crucial role in cell division. Here, we show evidence that expression of CDC16 in T-ALL is modulated at the transcriptional level by oncogenic Casein Kinase II (CK2) via direct phosphorylation of Ikaros, a tumor suppressor protein and transcription factor.",

year = "2019",

month = jul,

day = "1",

doi = "10.1158/1538-7445.SABCS18-4400",

language = "American English",

journal = "Cancer Research",

}

TY - JOUR

T1 - Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

AU - Raju, Pavan Kumar Dhanyam

AU - Kane, Shriya

AU - Gowda, Chandrika

AU - Song, Chunhua

AU - Ding, Yali

AU - Payne, Jonathan

AU - Iyer, Soumya

AU - Curry, Nathalia Moreno

AU - McGrath, Mary

AU - Bamme, Yevgeniya

AU - Tan, Bihua

AU - Soliman, Mario

AU - Desai, Dhimant

AU - Sharma, Arati

AU - Payne, Kimberly J.

AU - Dovat, Sinisa

N1 - Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA CDC16 is one of several subunits of the anaphase-promoting complex (APC) with crucial role in cell division. Here, we show evidence that expression of CDC16 in T-ALL is modulated at the transcriptional level by oncogenic Casein Kinase II (CK2) via direct phosphorylation of Ikaros, a tumor suppressor protein and transcription factor.

PY - 2019/7/1

Y1 - 2019/7/1

UR - https://cancerres.aacrjournals.org/content/79/13_Supplement/4400

U2 - 10.1158/1538-7445.SABCS18-4400

DO - 10.1158/1538-7445.SABCS18-4400

M3 - Meeting abstract

JO - Cancer Research

JF - Cancer Research

ER -

Abstract 4400: Epigenetic regulation of CDC16 expression by the ikaros and casein kinase II (CK2) in T-cell acute lymphoblastic leukemia (T-ALL)

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