A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies

Kofi N. Donkor; Hyeree Jang; Julie Hana Selim; Yevgeniya J. Ioffe; Linda J. Hong

doi:10.1177/10600280251320067

A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	877-890
Number of pages	14
Journal	Annals of Pharmacotherapy
Volume	59
Issue number	10
DOIs	https://doi.org/10.1177/10600280251320067
State	Published - Oct 2025

ASJC Scopus Subject Areas

Pharmacology (medical)

Keywords

corticosteroid prophylaxis
decadron
dexamethasone premedication
meta-analysis
paclitaxel hypersensitivity reaction
paclitaxel infusion reaction
paclitaxel toxicity
randomized controlled trial
steroid prophylaxis
systematic review
taxol hypersensitivity
Dexamethasone/administration & dosage
Administration, Oral
Humans
Histamine H2 Antagonists/administration & dosage
Paclitaxel/adverse effects
Randomized Controlled Trials as Topic
Antineoplastic Agents, Phytogenic/adverse effects
Administration, Intravenous
Genital Neoplasms, Female/drug therapy
Female
Drug Hypersensitivity/prevention & control

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Donkor, K. N., Jang, H., Selim, J. H., Ioffe, Y. J., & Hong, L. J. (2025). A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies. Annals of Pharmacotherapy, 59(10), 877-890. https://doi.org/10.1177/10600280251320067

A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies. / Donkor, Kofi N.; Jang, Hyeree ; Selim, Julie Hana et al.
In: Annals of Pharmacotherapy, Vol. 59, No. 10, 10.2025, p. 877-890.

Research output: Contribution to journal › Article › peer-review

Donkor, KN , Jang, H , Selim, JH , Ioffe, YJ & Hong, LJ 2025, 'A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies', Annals of Pharmacotherapy, vol. 59, no. 10, pp. 877-890. https://doi.org/10.1177/10600280251320067

Donkor KN , Jang H , Selim JH , Ioffe YJ , Hong LJ. A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies. Annals of Pharmacotherapy. 2025 Oct;59(10):877-890. doi: 10.1177/10600280251320067

Donkor, Kofi N. ; Jang, Hyeree ; Selim, Julie Hana et al. / A Randomized Controlled Trial Plus a Systematic Review and Meta-Analysis of Published Studies Evaluating a Conventional Prophylactic Regimen of Oral Dexamethasone vs Short-Course Intravenous Dexamethasone in Preventing Paclitaxel-Associated Hypersensitivity Reactions in Patients With Gynecologic Malignancies. In: Annals of Pharmacotherapy. 2025 ; Vol. 59, No. 10. pp. 877-890.

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ASJC Scopus Subject Areas

Keywords

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