TY - JOUR
T1 - A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with aids
AU - Hutcherson, Stephen L.
AU - Lanz, René
N1 - PURPOSE: To assess the efficacy of intravitreous fomivirsen sodium, an antisense oligonucleotide, for newly diagnosed peripheral cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS). DESIGN: Randomized treatment intervention clinical trial. METHODS: A multicenter, prospective, and randomized clinical trial compared immediate treatment of CMV retinitis with fomivirsen (165 μg administered intravitreously) to deferral of treatment until CMV retinitis lesions progressed by standard definitions.
PY - 2002
Y1 - 2002
UR - http://www.scopus.com/inward/record.url?scp=0036202668&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036202668&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(02)01327-2
DO - 10.1016/S0002-9394(02)01327-2
M3 - Article
SN - 0002-9394
VL - 133
SP - 467
EP - 474
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 4
ER -