Skip to main navigation Skip to search Skip to main content

A phase I trial of BKM120 (Buparlisib) in combination with fulvestrant in postmenopausal women with estrogen receptor-positive metastatic breast cancer

  • Cynthia X. Ma
  • , Jingqin Luo
  • , Michael Naughton
  • , Foluso Ademuyiwa
  • , Rama Suresh
  • , Malachi Griffith
  • , Obi L. Griffith
  • , Zachary L. Skidmore
  • , Nicholas C. Spies
  • , Avinash Ramu
  • , Lee Trani
  • , Timothy Pluard
  • , Gayathri Nagaraj
  • , Shana Thomas
  • , Zhanfang Guo
  • , Jeremy Hoog
  • , Jing Han
  • , Elaine Mardis
  • , Craig Lockhart
  • , Matthew J. Ellis

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1583-1591
Number of pages9
JournalClinical Cancer Research
Volume22
Issue number7
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

ASJC Scopus Subject Areas

  • General Medicine

Keywords

  • Phosphoinositide-3 Kinase Inhibitors
  • Aminopyridines/administration & dosage
  • Humans
  • Middle Aged
  • Morpholines/administration & dosage
  • Treatment Outcome
  • Antineoplastic Combined Chemotherapy Protocols/adverse effects
  • Biomarkers, Tumor
  • Fulvestrant
  • Receptors, Estrogen/metabolism
  • Estradiol/administration & dosage
  • Neoplasm Metastasis
  • PTEN Phosphohydrolase
  • Receptors, Progesterone
  • Postmenopause
  • Adult
  • Female
  • Aged
  • Breast Neoplasms/drug therapy

Cite this