A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals

Christoph Schaniel; Priyanka Dhanan; Bin Hu; Yuguang Xiong; Teeya Raghunandan; David M. Gonzalez; Rafael Dariolli; Sunita L. D'Souza; Arjun S. Yadaw; Jens Hansen; Gomathi Jayaraman; Bino Mathew; Moara Machado; Seth I. Berger; Joseph Tripodi; Vesna Najfeld; Jalaj Garg; Marc Miller; Colleen S. Surlyn; Katherine C. Michelis; Neelima C. Tangirala; Himali Weerahandi; David C. Thomas; Kristin G. Beaumont; Robert Sebra; Milind Mahajan; Eric Schadt; Dusica Vidovic; Stephan C. Schürer; Joseph Goldfarb; Evren U. Azeloglu; Marc R. Birtwistle; Eric A. Sobie; Jason C. Kovacic; Nicole C. Dubois; Ravi Iyengar

doi:10.1016/j.stemcr.2021.10.005

A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals

Christoph Schaniel, Priyanka Dhanan, Bin Hu, Yuguang Xiong, Teeya Raghunandan, David M. Gonzalez, Rafael Dariolli, Sunita L. D'Souza, Arjun S. Yadaw, Jens Hansen, Gomathi Jayaraman, Bino Mathew, Moara Machado, Seth I. Berger, Joseph Tripodi, Vesna Najfeld, Jalaj Garg, Marc Miller, Colleen S. Surlyn, Katherine C. MichelisNeelima C. Tangirala, Himali Weerahandi, David C. Thomas, Kristin G. Beaumont, Robert Sebra, Milind Mahajan, Eric Schadt, Dusica Vidovic, Stephan C. Schürer, Joseph Goldfarb, Evren U. Azeloglu, Marc R. Birtwistle, Eric A. Sobie, Jason C. Kovacic, Nicole C. Dubois, Ravi Iyengar

Medicine

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3036-3049
Number of pages	14
Journal	Stem Cell Reports
Volume	16
Issue number	12
DOIs	https://doi.org/10.1016/j.stemcr.2021.10.005
State	Published - Dec 14 2021

ASJC Scopus Subject Areas

Biochemistry
Genetics
Developmental Biology
Cell Biology

Keywords

age- and sex-independent gene signature
cardiomyocytes
clinically well-characterized healthy subjects
genetic variants of mild common disease phenotypes or more severe disease with incomplete penetrance
induced pluripotent stem cells
racially/ethnically diverse
similar physiology and transcriptomes
whole-genome sequencing

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Schaniel, C., Dhanan, P., Hu, B., Xiong, Y., Raghunandan, T., Gonzalez, D. M., Dariolli, R., D'Souza, S. L., Yadaw, A. S., Hansen, J., Jayaraman, G., Mathew, B., Machado, M., Berger, S. I., Tripodi, J., Najfeld, V., Garg, J., Miller, M., Surlyn, C. S., ... Iyengar, R. (2021). A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals. Stem Cell Reports, 16(12), 3036-3049. https://doi.org/10.1016/j.stemcr.2021.10.005

Schaniel, C, Dhanan, P, Hu, B, Xiong, Y, Raghunandan, T, Gonzalez, DM, Dariolli, R, D'Souza, SL, Yadaw, AS, Hansen, J, Jayaraman, G, Mathew, B, Machado, M, Berger, SI, Tripodi, J, Najfeld, V, Garg, J, Miller, M, Surlyn, CS, Michelis, KC, Tangirala, NC, Weerahandi, H, Thomas, DC, Beaumont, KG, Sebra, R, Mahajan, M, Schadt, E, Vidovic, D, Schürer, SC, Goldfarb, J, Azeloglu, EU, Birtwistle, MR, Sobie, EA, Kovacic, JC, Dubois, NC & Iyengar, R 2021, 'A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals', Stem Cell Reports, vol. 16, no. 12, pp. 3036-3049. https://doi.org/10.1016/j.stemcr.2021.10.005

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author = "Christoph Schaniel and Priyanka Dhanan and Bin Hu and Yuguang Xiong and Teeya Raghunandan and Gonzalez, {David M.} and Rafael Dariolli and D'Souza, {Sunita L.} and Yadaw, {Arjun S.} and Jens Hansen and Gomathi Jayaraman and Bino Mathew and Moara Machado and Berger, {Seth I.} and Joseph Tripodi and Vesna Najfeld and Jalaj Garg and Marc Miller and Surlyn, {Colleen S.} and Michelis, {Katherine C.} and Tangirala, {Neelima C.} and Himali Weerahandi and Thomas, {David C.} and Beaumont, {Kristin G.} and Robert Sebra and Milind Mahajan and Eric Schadt and Dusica Vidovic and Sch{\"u}rer, {Stephan C.} and Joseph Goldfarb and Azeloglu, {Evren U.} and Birtwistle, {Marc R.} and Sobie, {Eric A.} and Kovacic, {Jason C.} and Dubois, {Nicole C.} and Ravi Iyengar",

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AU - Schaniel, Christoph

AU - Dhanan, Priyanka

AU - Hu, Bin

AU - Xiong, Yuguang

AU - Raghunandan, Teeya

AU - Gonzalez, David M.

AU - Dariolli, Rafael

AU - D'Souza, Sunita L.

AU - Yadaw, Arjun S.

AU - Hansen, Jens

AU - Jayaraman, Gomathi

AU - Mathew, Bino

AU - Machado, Moara

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AU - Tripodi, Joseph

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AU - Surlyn, Colleen S.

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AU - Tangirala, Neelima C.

AU - Weerahandi, Himali

AU - Thomas, David C.

AU - Beaumont, Kristin G.

AU - Sebra, Robert

AU - Mahajan, Milind

AU - Schadt, Eric

AU - Vidovic, Dusica

AU - Schürer, Stephan C.

AU - Goldfarb, Joseph

AU - Azeloglu, Evren U.

AU - Birtwistle, Marc R.

AU - Sobie, Eric A.

AU - Kovacic, Jason C.

AU - Dubois, Nicole C.

AU - Iyengar, Ravi

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KW - induced pluripotent stem cells

KW - racially/ethnically diverse

KW - similar physiology and transcriptomes

KW - whole-genome sequencing

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A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals

ASJC Scopus Subject Areas

Keywords

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