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8-Isoprostane increases scavenger receptor A and matrix metalloproteinase activity in THP-1 macrophages, resulting in long-lived foam cells

  • H. Scholz
  • , P. Aukrust
  • , J. K. Damås
  • , S. Tonstad
  • , E. L. Sagen
  • , S. O. Kolset
  • , C. Hall
  • , A. Yndestad
  • , B. Halvorsen

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)451-458
Number of pages8
JournalEuropean Journal of Clinical Investigation
Volume34
Issue number7
DOIs
StatePublished - Jul 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Clinical Biochemistry

Keywords

  • Apoptosis
  • Atherosclerosis
  • Free radicals
  • Macrophages
  • Matrix metalloproteinases
  • Oxidative Stress/physiology
  • Tissue Inhibitor of Metalloproteinase-1/metabolism
  • Matrix Metalloproteinase 9/metabolism
  • Dinoprost/analogs & derivatives
  • Humans
  • Receptors, Immunologic/metabolism
  • Blotting, Western
  • Caspases/metabolism
  • Receptors, Scavenger
  • Vasoconstrictor Agents/pharmacology
  • Foam Cells/drug effects

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