135 EFFECTS OF AGING AND THE ANTIHYPERTENSIVE DRUG RILMENIDINE ON NERVE GROWTH FACTOR EXPRESSION IN THE SPLEEN OF MALE F344 RATS.

J. Gross; S. Vyas; C. A. Molinaro; S. Perez; B. Millar; J. Carter; S. Flowers; S. ThyagaRajan; D. L. Bellinger

doi:10.1097/00042871-200701010-00143

135 EFFECTS OF AGING AND THE ANTIHYPERTENSIVE DRUG RILMENIDINE ON NERVE GROWTH FACTOR EXPRESSION IN THE SPLEEN OF MALE F344 RATS.

J. Gross, S. Vyas, C. A. Molinaro, S. Perez, B. Millar, J. Carter, S. Flowers, S. ThyagaRajan, D. L. Bellinger

Anatomy Division

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Original language	American English
Journal	Journal of Investigative Medicine
Volume	55
DOIs	https://doi.org/10.1097/00042871-200701010-00143
State	Published - Jan 1 2007

Disciplines

Medicine and Health Sciences
Endocrinology, Diabetes, and Metabolism
Endocrinology
Internal Medicine

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title = "135 EFFECTS OF AGING AND THE ANTIHYPERTENSIVE DRUG RILMENIDINE ON NERVE GROWTH FACTOR EXPRESSION IN THE SPLEEN OF MALE F344 RATS.",

author = "J. Gross and S. Vyas and Molinaro, {C. A.} and S. Perez and B. Millar and J. Carter and S. Flowers and S. ThyagaRajan and Bellinger, {D. L.}",

note = "Previous research in our laboratory showed an age-related decline in noradrenergic (NA) sympathetic innervation of spleens from male Fischer 344 (F344) rats. Since nerve growth factor (NGF) plays an important role in determining the density of sympathetic innervation of target tissues throughout life, dysregulation of NGF expression in splenic target cells might explain the loss of sympathetic nerves.",

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AU - Gross, J.

AU - Vyas, S.

AU - Molinaro, C. A.

AU - Perez, S.

AU - Millar, B.

AU - Carter, J.

AU - Flowers, S.

AU - ThyagaRajan, S.

AU - Bellinger, D. L.

N1 - Previous research in our laboratory showed an age-related decline in noradrenergic (NA) sympathetic innervation of spleens from male Fischer 344 (F344) rats. Since nerve growth factor (NGF) plays an important role in determining the density of sympathetic innervation of target tissues throughout life, dysregulation of NGF expression in splenic target cells might explain the loss of sympathetic nerves.

PY - 2007/1/1

Y1 - 2007/1/1

UR - https://jim.bmj.com/content/jim/55/1/S99.2.full.pdf

U2 - 10.1097/00042871-200701010-00143

DO - 10.1097/00042871-200701010-00143

M3 - Article

VL - 55

JO - Journal of Investigative Medicine

JF - Journal of Investigative Medicine

ER -

135 EFFECTS OF AGING AND THE ANTIHYPERTENSIVE DRUG RILMENIDINE ON NERVE GROWTH FACTOR EXPRESSION IN THE SPLEEN OF MALE F344 RATS.

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