@article{a6fbfbdab5de437f8cf80cc43d045b30,
title = "1-Naphthylmethylphosphonic acid derivatives as osteoclastic acid phosphatase inhibitors",
author = "Schwender, \{Charles F.\} and Beers, \{Scott A.\} and Elizabeth Malloy and Keith Demarest and Lisa Minor and Lau, \{K. H.W.\}",
note = "Inhibition of the enzyme, osteoclastic acid phosphatase (OAP) may be a viable approach to the treatment of osteoporosis. A series of arylmethylphosphonic acids were synthesized and shown to be inhibitors of OAP. The most potent inhibitor, bis -benzoyl-1-naphthylmethylphosphonic acid ( 7a) had an IC 50 = 1.4 μM.",
year = "1995",
month = aug,
day = "17",
doi = "10.1016/0960-894X(95)00299-9",
language = "English",
volume = "5",
pages = "1801--1806",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
number = "16",
}