0657 Circadian and Homeostatic Control of The Sleep-wake Cycle In Type 2 Diabetes Correlated with salivary Melatonin

P Cavalcanti Ferreira; L Berk; Noha S. Daher; J Petrofsky; E Lohman; A John; T Campus

doi:10.1093/SLEEP/ZSY061.656

0657 Circadian and Homeostatic Control of The Sleep-wake Cycle In Type 2 Diabetes Correlated with salivary Melatonin

P Cavalcanti Ferreira
, L Berk
, Noha S. Daher
, J Petrofsky
, E Lohman
, A John
, T Campus

Loma Linda University

Research output: Contribution to journal › Meeting abstract › peer-review

Abstract

Introduction: The purpose of this study was to assess the changes in the circadian and homeostatic control of the sleep-wake cycle in type 2 diabetes mellitus (T2DM) and correlate the findings with salivary melatonin levels. Methods: The study cohorts were 21 subjects with a diagnosis of T2DM of more than one year and 21 healthy subjects age and gender matched. Subjects were assessed by the Beck's Depression Inventory (BDI), the Apnea Risk Evaluation System (ARES) questionnaire, hemoglobin A1c (HbA1c), actigraphy and salivary melatonin levels. Results: Melatonin levels at bed time were significantly lower in diabetic subjects than healthy controls (11.7 ± 7.2pg/mL vs. 24.1 ± 10.8pg/ mL; p

Original language	American English
Pages (from-to)	A244-A244
Journal	Sleep
Volume	41
Issue number	suppl_1
DOIs	https://doi.org/10.1093/SLEEP/ZSY061.656
State	Published - Apr 27 2018

Disciplines

Anesthesiology
Psychology
Endocrinology, Diabetes, and Metabolism
Internal Medicine
Endocrinology

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abstract = "Introduction: The purpose of this study was to assess the changes in the circadian and homeostatic control of the sleep-wake cycle in type 2 diabetes mellitus (T2DM) and correlate the findings with salivary melatonin levels. Methods: The study cohorts were 21 subjects with a diagnosis of T2DM of more than one year and 21 healthy subjects age and gender matched. Subjects were assessed by the Beck's Depression Inventory (BDI), the Apnea Risk Evaluation System (ARES) questionnaire, hemoglobin A1c (HbA1c), actigraphy and salivary melatonin levels. Results: Melatonin levels at bed time were significantly lower in diabetic subjects than healthy controls (11.7 ± 7.2pg/mL vs. 24.1 ± 10.8pg/ mL; p",

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AU - Ferreira, P Cavalcanti

AU - Berk, L

AU - Daher, Noha S.

AU - Petrofsky, J

AU - Lohman, E

AU - John, A

AU - Campus, T

N1 - AbstractIntroduction. The purpose of this study was to assess the changes in the circadian and homeostatic control of the sleep-wake cycle in type 2 diabetes m

PY - 2018/4/27

Y1 - 2018/4/27

N2 - Introduction: The purpose of this study was to assess the changes in the circadian and homeostatic control of the sleep-wake cycle in type 2 diabetes mellitus (T2DM) and correlate the findings with salivary melatonin levels. Methods: The study cohorts were 21 subjects with a diagnosis of T2DM of more than one year and 21 healthy subjects age and gender matched. Subjects were assessed by the Beck's Depression Inventory (BDI), the Apnea Risk Evaluation System (ARES) questionnaire, hemoglobin A1c (HbA1c), actigraphy and salivary melatonin levels. Results: Melatonin levels at bed time were significantly lower in diabetic subjects than healthy controls (11.7 ± 7.2pg/mL vs. 24.1 ± 10.8pg/ mL; p

AB - Introduction: The purpose of this study was to assess the changes in the circadian and homeostatic control of the sleep-wake cycle in type 2 diabetes mellitus (T2DM) and correlate the findings with salivary melatonin levels. Methods: The study cohorts were 21 subjects with a diagnosis of T2DM of more than one year and 21 healthy subjects age and gender matched. Subjects were assessed by the Beck's Depression Inventory (BDI), the Apnea Risk Evaluation System (ARES) questionnaire, hemoglobin A1c (HbA1c), actigraphy and salivary melatonin levels. Results: Melatonin levels at bed time were significantly lower in diabetic subjects than healthy controls (11.7 ± 7.2pg/mL vs. 24.1 ± 10.8pg/ mL; p

UR - https://academic.oup.com/sleep/article/41/suppl_1/A244/4988695

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JO - Sleep

JF - Sleep

IS - suppl_1

ER -

0657 Circadian and Homeostatic Control of The Sleep-wake Cycle In Type 2 Diabetes Correlated with salivary Melatonin

Abstract

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